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Stadt Ulm, Deutschland


Prof. Dr. Karin Scharffetter-Kochanek
Klinik für Dermatologie und Allergologie
Albert-Einstein-Allee 23
89081 Ulm


Prof. Dr. Hartmut Geiger
Klinik für Dermatologie und Allergologie
Universität Ulm
James Franck-Ring 11c
89081 Ulm

Clinical Research Unit (KFO 142) -

Molecular and cellular aging – from mechanisms to clinical perspectives

Aging can be described as a continual loss of specific organ functions with an age-associated increase in morbidity and mortality. It is known, if not in molecular detail, that intrinsic and extrinsic aging processes are regulated through genetic factors, complex “cross-talk” among signal transduction cascades and a variety of environmental factors.

The goal of this clinical research group is to define the intrinsic and extrinsic aging mechanisms and to develop novel preventative and/or therapeutic strategies which will enable “healthy aging”. Therefore, these nine projects provide a mechanistic, preclinical approach to elucidate the causative factors which drive the aging process and the corresponding use of this information in a prospective clinical setting.

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